Objective:To investigate the predictive value of tumor volume in CT urography(CTU)three-di-mensional mode for recurrence of non-muscle invasive bladder cancer.Methods:The data of 124 patients who under-went transurethral resection of bladder tumor from January 2016 to March 2020 were retrospectively analyzed.All of the patients received CTU,the region of interest was delineated in the three-dimensional mode constructed by CTU,the length,width and height of the tumor were measured,and the effective tumor volume(TV)was calculated using the formula.According to the 2-year follow-up results,they were divided into recurrence group(n=25)and non-re-currence group(n=99).Univariate analysis was used to compare the differences in clinical data between the two groups,and unconditional Logistic regression analysis was performed for significant factors.The receiver operating characteristic(ROC)curve was used to calculate the area under the curve(AUC)of independent predictors,and the optimal cut-off value and corresponding sensitivity and specificity were analyzed.Results:In 124 patients,the recur-rence rates of 3 months and 2 years after operation were 4.8%(6/124)and 20.1%(25/124),respectively.The tumor volume[2.9(1.8,4.7)cm3]and proportion of high-grade tumors(40%)in the recurrence group were higher than those in the non-recurrence group[1.4(0.6,2.3)cm3,20%],the differences were statistically significant(P=0.04,P=0.03).Conclusion:Tumor volume can be used as an independent predictor of postoperative tumor recurrence.