妇科恶性肿瘤患者术后下肢深静脉血栓形成的中医证型分布及风险预测
Distribution of traditional Chinese medicine syndrome types and risk prediction of postoperative deep vein thrombosis in patients with gynecologic malignant tumor
赵婧冰 1赖雅薇 1梁菲梅 2李道成 2周英2
作者信息
- 1. 广州中医药大学第一临床医学院,广东广州 510000
- 2. 广州中医药大学第一附属医院妇儿中心三妇科,广东广州 510000
- 折叠
摘要
目的 分析妇科恶性肿瘤患者术后下肢深静脉血栓(DVT)的中医证型分布及风险预测.方法 收集 2019 年1月至 2022 年 9 月于广州中医药大学第一附属医院行妇科恶性肿瘤手术的 279 例患者的临床资料进行回顾性分析,根据术后是否发生DVT分为血栓组(40 例)和非血栓组(239 例),分析两组中医证型分布情况及DVT相关危险因素.结果 妇科恶性肿瘤术后DVT的发生率为14.34%,血栓组气滞血瘀证占比最大(40.0%).多因素分析提示,年龄、既往无手术史、术后 3 d D-二聚体(DD)水平是妇科恶性肿瘤术后DVT的独立危险因素(P<0.05).三指标联合的受试者工作特征曲线下面积为 0.776(95%CI:0.697～0.855),经Hosmer-Lemeshow检验该模型准确性良好.结论 妇科恶性肿瘤术后DVT以气滞血瘀证最为常见,高龄、既往无手术史、术后 3 d DD高水平是该病的独立危险因素,三指标联合有较好的预测效率.临床应重视术后及时检测相关指标,以预防妇科恶性肿瘤术后DVT.
Abstract
Objective To analyze the distribution of traditional Chinese medicine(TCM)syndrome types and risk prediction of postoperative deep vein thrombosis(DVT)in patients with gynecologic malignant tumor.Methods Clinical data of 279 patients with gynecologic malignant tumor undergoing surgery in the First Affiliated Hospital of Guangzhou University of Chinese Medicine from January 2019 to September 2022 were retrospectively analyzed.All the patients were divided into the thrombus group(40 cases)and the non-thrombus group(239 cases)according to the occurrence of DVT after surgery.The distribution of TCM syndrome types between the two groups and related risk factors of DVT were analyzed.Results The incidence rate of postoperative DVT of gynecologic malignant tumor was 14.34% ,and the highest proportion was qi stagnation and blood stasis syndrome(40.0% )in the thrombus group.The results of multivariate analysis showed that age,without previous history of surgery and the D-dimer(DD)level of postoperative 3 days were the independent risk factors for postoperative DVT of gynecologic malignant tumor(P<0.05).The area under the receiver operating characteristic curve of the combination of three indicators was 0.776(95% CI:0.697-0.855),and Hosmer-lemeshow test showed that the accuracy of the model was good.Conclusion The qi stagnation and blood stasis syndrome is the most common syndrome type of postoperative DVT of gynecologic malignant tumor.The advanced age,without previous history of surgery and high DD level of postoperative 3 days are the independent risk factors of postoperative DVT of gynecologic malignant tumor,and the combination of three indicators has good predictive efficiency.In clinical practice,timely detection of relevant indicators after surgery should be emphasized to prevent postoperative DVT of gynecologic malignant tumor.
关键词
下肢深静脉血栓/妇科恶性肿瘤/中医证型/风险预测Key words
Deep vein thrombosis/Gynecologic malignant tumor/Traditional Chinese Medicine syndrome type/Risk prediction引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据