妇儿健康导刊2024,Vol.3Issue(5) :15-17,24.

左旋甲状腺素抑制疗法在女性桥本甲状腺炎治疗中的应用效果

Application effect of Levothyroxine suppression therapy in the treatment of female hashimoto thyroiditis

辛梦
妇儿健康导刊2024,Vol.3Issue(5) :15-17,24.

左旋甲状腺素抑制疗法在女性桥本甲状腺炎治疗中的应用效果

Application effect of Levothyroxine suppression therapy in the treatment of female hashimoto thyroiditis

辛梦1
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作者信息

  • 1. 山东省枣庄市薛城区临城街道社区卫生服务中心全科门诊,山东枣庄 277000
  • 折叠

摘要

目的 探讨左旋甲状腺素抑制疗法在女性桥本甲状腺炎治疗中的应用效果.方法 选取 2020 年1月至 2022 年 3 月在山东省枣庄市薛城区临城街道社区卫生服务中心诊治的 60 例桥本甲状腺炎女性患者作为研究对象,按照随机抽签法分为对照组(30 例)、观察组(30 例).对照组给予甲状腺片,观察组给予左旋甲状腺素抑制疗法,比较两组临床疗效、甲状腺功能.结果 观察组临床总有效率较对照组高(P<0.05);治疗后观察组游离甲状腺素、游离三碘甲状腺原氨酸水平高于对照组,促甲状腺激素低于对照组(P<0.05);观察组治疗后抗甲状腺过氧化物酶自身抗体、抗甲状腺球蛋白抗体水平低于对照组(P<0.05);两组不良反应总发生率比较,差异无统计学意义(P>0.05).结论 左旋甲状腺素抑制疗法在女性桥本甲状腺炎治疗中的应用效果较好.

Abstract

Objective To investigate the application effect of Levothyroxine suppression therapy in the treatment of female hashimoto thyroiditis.Methods A total of 60 female patients with hashimoto thyroiditis who were diagnosed and treated in Xuecheng District Lincheng Street Community Health Service Center in Zaozhuang City,Shandong Province from January 2020 to March 2022 were selected as the research objects.According to the random lottery method,they were divided into the control group(30 cases)and the observation group(30 cases).The control group was given Thyroid Tablets,and the observation group was given Levothyroxine suppression therapy.The clinical efficacy and thyroid function of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the levels of free thyroxine and free triiodothyronine in the observation group were higher than those in the control group,and thyroid stimulating hormone was lower than that in the control group(P<0.05).The levels of anti-thyroid peroxidase autoantibody and anti-thyroglobulin antibody in the observation group were lower than those in the control group after treatment(P<0.05).There was no statistically significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Levothyroxine suppression therapy is effective in the treatment of female hashimoto thyroiditis.

关键词

左旋甲状腺素抑制疗法/女性/桥本甲状腺炎/甲状腺功能

Key words

Levothyroxine suppression therapy/Female/Hashimoto thyroiditis/Thyroid function

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出版年

2024
妇儿健康导刊
婚姻与家庭杂志社

妇儿健康导刊

ISSN:2097-115X
参考文献量16
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