Objective To investigate the clinical effect of sequential antibiotic therapy in the treatment of bronchopneumonia in children.Methods A total of 113 children with bronchopneumonia admitted to the First People's Hospital of Longxi County from August 2021 to October 2022 were selected as the study objects and divided into the control group(56 cases)and the experimental group(57 cases)according to the random number table method.The control group received conventional treatment,and the experimental group received sequential antibiotic therapy.The therapeutic effect,white blood cell count,C-reactive protein level,clinical symptom disappearance time,total incidence of adverse reactions and inflammatory factor levels were compared between the two groups.Results The total effective rate of the experimental group was higher than that of the control group(P<0.05).After treatment,white blood cell count and C-reactive protein level in the experimental group were lower than those in the control group(P<0.05).The disappearance time of clinical symptoms in the experimental group was shorter than that in the control group(P<0.05).The total incidence of adverse reactions in the experimental group was lower than that in the control group(P<0.05).The levels of interferon-γ,tumor necrosis factor-α and interleukin-6 in the experimental groups were lower than those in the control group(P<0.05).Conclusion The clinical effect of sequential antibiotic therapy in the treatment of bronchopneumonia in children is precise,it can accelerate the improvement of clinical symptoms,reduce the levels of white blood cell count,C-reactive protein and inflammatory factors,and it is safe and worthy of clinical promotion.
关键词
抗生素序贯疗法/小儿支气管肺炎/白细胞计数/C反应蛋白
Key words
Sequential antibiotic therapy/Bronchopneumonia in children/White blood cell count/C-reactive protein
维普
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