妇儿健康导刊2024,Vol.3Issue(5) :102-104,111.

布地奈德结合头孢哌酮舒巴坦钠治疗新生儿肺炎的临床效果

Clinical effect of Budesonide combined with Cefoperazone Sulbactam Sodium in the treatment of neonatal pneumonia

师林夏 王静
妇儿健康导刊2024,Vol.3Issue(5) :102-104,111.

布地奈德结合头孢哌酮舒巴坦钠治疗新生儿肺炎的临床效果

Clinical effect of Budesonide combined with Cefoperazone Sulbactam Sodium in the treatment of neonatal pneumonia

师林夏 1王静2
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作者信息

  • 1. 陕西省韩城市妇幼保健院新生儿科,陕西韩城 715400
  • 2. 陕西省韩城市人民医院新生儿科,陕西韩城 715400
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摘要

目的 探讨布地奈德结合头孢哌酮舒巴坦钠治疗新生儿肺炎的临床效果.方法 选取2019 年1月至 2023 年 3 月韩城市妇幼保健院及韩城市人民医院治疗的 60 例肺炎患儿作为研究对象,按照单双数法分为对照组(30 例)与观察组(30 例).对照组采用头孢哌酮舒巴坦钠治疗,观察组在对照组基础上结合布地奈德治疗,比较两组临床疗效、炎症因子水平和临床治疗指标.结果 观察组治疗总有效率高于对照组(P<0.05);治疗后,两组C反应蛋白、降钙素原、中性粒细胞百分比水平均降低,且观察组低于对照组(P<0.05);观察组肺部啰音完全消失时间、胸部X线片病灶吸收时间、血气分析恢复正常时间、住院时间均短于对照组(P<0.05).结论 布地奈德结合头孢哌酮舒巴坦钠治疗新生儿肺炎可提高临床疗效,降低炎症因子水平,改善临床治疗指标,值得推广使用.

Abstract

Objective To explore the clinical effect of Budesonide combined with Cefoperazone Sulbactam Sodium in the treatment of neonatal pneumonia.Methods A total of 60 children with pneumonia admitted to Hancheng Maternal and Child Health Hospital and Hancheng People's Hospital from January 2019 to March 2023 were selected as the study objects.All the children were divided into the control group(30 cases)and the observation group(30 cases)according to the odd-even number method.The control group was treated with Cefoperazone Sulbactam Sodium,and the observation group was treated with Budesonide on the basis of the control group.The clinical efficacy,levels of inflammatory factors and clinical therapeutic indexes of the two groups were compared.Results The total effective rate of treatment in the observation group was higher than that in the control group(P<0.05).After treatment,the levels of C-reactive protein,procalcitonin and percent neutrophils in the two groups were both reduced,and the observation group was lower than the control group(P<0.05).The time for complete disappearance of lung rales,absorption time of chest X-ray lesions,time for blood gas analysis to return to normal and hospital stay in the observation group were shorter than those in the control group(P<0.05).Conclusion The combination of Budesonide and Cefoperazone Sulbactam Sodium in the treatment of neonatal pneumonia can improve clinical efficacy,reduce the level of inflammatory factors and improve clinical treatment indicators,which is worth promoting and using.

关键词

布地奈德/头孢哌酮舒巴坦钠/新生儿肺炎/C反应蛋白/降钙素原

Key words

Budesonide/Cefoperazone Sulbactam Sodium/Neonatal pneumonia/C-reactive protein/Procalcitonin

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出版年

2024
妇儿健康导刊
婚姻与家庭杂志社

妇儿健康导刊

ISSN:2097-115X
参考文献量16
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