妇儿健康导刊2024，Vol.3Issue(5) ：108-111.

低剂量盐酸艾司氯胺酮在孕产妇腰硬联合麻醉剖宫产术中的应用效果

Application effect of low dose of Esketamine Hydrochloride in combined spinal and epidural anesthesia for cesarean section in pregnant and parturient women

高亚男
妇儿健康导刊2024，Vol.3Issue(5) ：108-111.
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  • 万方数据

低剂量盐酸艾司氯胺酮在孕产妇腰硬联合麻醉剖宫产术中的应用效果

Application effect of low dose of Esketamine Hydrochloride in combined spinal and epidural anesthesia for cesarean section in pregnant and parturient women

高亚男1
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作者信息

  • 1. 北京市大兴区妇幼保健院麻醉科,北京 102600
  • 折叠

摘要

目的 探讨低剂量盐酸艾司氯胺酮在孕产妇腰硬联合麻醉剖宫产术中的应用效果.方法 选取2023 年1月至 6 月于北京市大兴区妇幼保健院行剖宫产术的100 例孕产妇作为研究对象,按照随机数字表法分为对照组和试验组,每组各 50 例.两组均采取腰硬联合麻醉,试验组静脉注射盐酸艾司氯胺酮,对照组静脉注射咪达唑仑,比较两组麻醉起效及恢复时间、麻醉效果和不良反应发生情况.结果 两组感觉阻滞起效、运动阻滞起效、感觉恢复和运动恢复时间比较,差异无统计学意义(P>0.05);试验组麻醉优良率高于对照组,差异有统计学意义(P<0.05);试验组不良反应总发生率低于对照组,差异有统计学意义(P<0.05).结论 低剂量盐酸艾司氯胺酮在腰硬联合麻醉剖宫产术中的应用效果较好,不良反应较少,值得临床推广.

Abstract

Objective To explore the application effect of low dose of Esketamine Hydrochloride in combined spinal and epidural anesthesia for cesarean section in pregnant and parturient women.Methods A total of 100 pregnant and parturient women undergoing cesarean section in Daxing District Maternal and Child Health Hospital of Beijing from January to June 2023 were selected as the study objects.All the pregnant and parturient women were divided into the control group and the experimental group using the random number table method,with 50 cases in each group.Both groups received combined spinal and epidural anesthesia,the experimental group received intravenous injection of Esketamine Hydrochloride,and the control group received intravenous injection of Midazolam.The time of anesthesia effective and recovery,anesthesia effects and the incidence of adverse reactions were compared between the two groups.Results There was no significant difference in the time of sensory block effective,motor block effective,sensory recovery and motor recovery between the two groups(P>0.05).The excellent anesthesia effects rate of the experimental group was higher than that of the control group,and the difference was statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of low dose of Esketamine Hydrochloride in combined spinal and epidural anesthesia for cesarean section has a good effect,fewer adverse reactions,which is worthy of clinical promotion.

关键词

盐酸艾司氯胺酮/腰硬联合麻醉/剖宫产术/麻醉效果

Key words

Esketamine Hydrochloride/Combined spinal and epidural anesthesia/Cesarean section/Anesthetic effect

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出版年

2024
妇儿健康导刊
婚姻与家庭杂志社

妇儿健康导刊

ISSN：2097-115X
参考文献量15
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