摘要
目的 分析新生儿高胆汁酸血症(HBA)预后的影响因素.方法 选取 2020 年1月至 2023年3 月深圳市宝安区松岗人民医院收治的167 例HBA新生儿为研究对象,按照预后情况分为预后良好组(150 例)与预后不良组(17 例),分析影响预后的因素.结果 母孕期HBA、早产、静脉营养≥7 d、合并感染及生化指标异常是影响HBA新生儿预后的独立危险因素(P<0.05);出生体重、胎龄是影响HBA新生儿预后的保护因素(P<0.05).结论 新生儿HBA不良预后与母孕期HBA、早产、静脉营养≥7 d、合并感染及生化指标升高有关,临床应予以重视,并针对低出生体重儿、早产儿做好相应预防工作.
Abstract
Objective To analyze the influencing factors on the prognosis of hyperbileacidemia(HBA)in newborns.Methods A total of 167 newborns with HBA in Songgang People's Hospital of Bao'an District,Shenzhen from January 2020 to March 2023 were selected as the study objects.According to the prognosis,they were divided into good prognosis group(150 cases)and poor prognosis group(17 cases),and the factors affecting prognosis were analyzed.Results Maternal HBA during pregnancy,premature delivery,intravenous nutrition≥7 days,co-infection,and abnormal biochemical indexes were independent risk factors affecting the prognosis of HBA in newborns(P<0.05).Birth weight and gestational age were protective factors affecting the prognosis of HBA in newborns(P<0.05).Conclusion Poor prognosis of neonatal HBA is related to maternal HBA during pregnancy,premature delivery,intravenous nutrition≥7 days,co-infection,and abnormal biochemical indexes,which should be paid attention clinically,and corresponding prevention work should be done for low birth weight infants and premature infants.
国家科技期刊平台
NSTL
维普
万方数据