头孢噻肟钠舒巴坦钠联合氨溴特罗口服溶液治疗小儿肺炎的临床效果
Clinical effect of Cefotaxime Sodium Sulbactam Sodium combined with Ambrocol Oral Solution in the treatment of children with pneumonia
宋伟艳1
作者信息
- 1. 山东省莱州市三山岛街道社区卫生服务中心药剂科,山东莱州 261400
- 折叠
摘要
目的 探讨头孢噻肟钠舒巴坦钠联合氨溴特罗口服溶液治疗小儿肺炎的临床效果.方法 选取2020年2月至2022年4月山东省莱州市三山岛街道社区卫生服务中心治疗的80例肺炎患儿作为研究对象,采用掷硬币法分为参照组(40 例)和研究组(40 例).参照组采用氨溴特罗口服溶液治疗,研究组采用头孢噻肟钠舒巴坦钠联合氨溴特罗口服溶液治疗,比较两组临床疗效、临床症状消失时间和住院时间、不良反应发生情况及炎症因子水平.结果 研究组治疗总有效率高于参照组,差异有统计学意义(P<0.05).研究组气喘、肺部啰音、发热和咳嗽消失时间及住院时间均短于参照组,差异有统计学意义(P<0.05).研究组不良反应总发生率低于参照组,差异有统计学意义(P<0.05).治疗后,研究组白细胞介素-8、肿瘤坏死因子-α及白细胞介素-6 水平低于参照组,差异有统计学意义(P<0.05).结论 小儿肺炎采用头孢噻肟钠舒巴坦钠联合氨溴特罗口服溶液治疗,可提高临床疗效,有效缩短临床症状消失时间及住院时间,减少不良反应,降低炎症因子水平,值得推广.
Abstract
Objective To explore the clinical effect of Cefotaxime Sodium Sulbactam Sodium combined with Ambrocol Oral Solution in the treatment of children with pneumonia.Methods A total of 80 children with pneumonia admitted to Sanshandao Community Health Service Center in Laizhou City,Shandong Province from February 2020 to April 2022 were selected as the study objects.All the children were divided into the reference group(40 cases)and the study group(40 cases)according to the coin toss method.The reference group was treated with Ambrocol Oral Solution,and the study group was treated with Cefotaxime Sodium Sulbactam Sodium combined with Ambrocol Oral Solution.The clinical efficacy,time of clinical symptom disappearance and hospitalization,incidence of adverse reactions,and inflammation factors were compared between the two groups.Results The total effective rate of treatment in the study group was higher than that in the reference group,and the difference was statistically significant(P<0.05).The disappearance time of asthma,lung rales,fever,and cough and hospitalization time in the study group were shorter than those in the reference group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the study group was lower than that in the reference group,and the difference was statistically significant(P<0.05).After treatment,the levels of interleukin-8,tumor necrosis factor-α,and interleukin-6 in the study group were lower than those in the reference group,and the differences were statistically significant(P<0.05).Conclusion The use of Cefotaxime Sodium Sulbactam Sodium combined with Ambrocol Oral Solution in the treatment of children with pneumonia can improve clinical efficacy,effectively shorten the disappearance time of clinical symptoms and hospitalization time,reduce adverse reactions and the levels of inflammation factors,which is worthy of promotion.
关键词
头孢噻肟钠舒巴坦钠/氨溴特罗口服溶液/小儿肺炎/不良反应Key words
Cefotaxime Sodium Sulbactam Sodium/Ambrocol Oral Solution/Children with pneumonia/Adverse reaction引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据