Objective To observe the application effect of humanized nursing in patients with hysteromyoma.Methods A total of 90 patients with hysteromyoma in Ningjin County Family Planning Maternal and Child Health Service Center from January to December 2022 were selected and divided into two groups by the random number table method.The control group(45 cases)was given routine nursing,and the observation group(45 cases)was given humanized nursing.The satisfaction and psychological status of the two groups were compared.Results The total nursing satisfaction rate,anxiety score,and depression score in the observation group were better than those in the control group,the differences were statistically significant(P<0.05).Conclusion Humanized nursing in the nursing of patients with hysteromyoma can better improve the nursing satisfaction of patients and promote the alleviation of negative emotions,which is worth promoting and applying.