Objective To explore the application value of individualized nursing in the nursing of patients with vaginitis.Methods A total of 88 patients with vaginitis treated in Heze Sixth People's Hospital from June 2021 to June 2023 were selected as the study subjects,and they were grouped by the random number table method,44 patients in the control group received routine care,and 44 patients in the experimental group received individualized nursing.The satisfaction,nursing compliance,and mastery of nursing knowledge were compared between the two groups.Results The scores of patients'satisfaction,nursing compliance,and nursing knowledge mastery in the experimental group were higher than those in the control group(P<0.05).Conclusion The application of individualized nursing in the nursing of patients with vaginitis can enhance patients'satisfaction and nursing compliance,and strengthen patients'knowledge mastery of nursing.