妊娠糖尿病对母亲及子代影响的研究进展
Research progress on the effect of gestational diabetes mellitus on mothers and offspring
陈丹丹 1林小娜1
作者信息
- 1. 浙江大学医学院附属邵逸夫医院妇产科,浙江杭州 310000
- 折叠
摘要
妊娠糖尿病(GDM)是一种常见的妊娠并发症,全球发病率呈上升趋势.GDM会增加不良围产期结局的发生风险,严重影响母亲及子代健康.母亲患有GDM的子代日后患 2 型糖尿病和代谢综合征的风险会增高,可能会面临肥胖、代谢性疾病、心血管系统发育异常和认知功能受损等问题.本文综述GDM的相关特征及影响,探讨其表观遗传学等潜在机制,旨在为有效控制和管理GDM提供一定的参考和帮助.
Abstract
Gestational diabetes mellitus(GDM)is a common pregnancy complication with an increasing global incidence.GDM increases the risk of adverse perinatal outcomes and severely affects the health of mothers and their offspring.The offspring of mothers with GDM will have an elevated risk of type 2 diabetes and metabolic syndrome later in life,and may encounter issues such as obesity,metabolic diseases,cardiovascular system developmental abnormalities,and impaired cognitive function.This article reviews the relevant characteristics and impacts of GDM,discusses potential mechanisms including epigenetics,and aims to provide reference and assistance for effective control and management of GDM.
关键词
妊娠糖尿病/母亲/子代Key words
Gestational diabetes mellitus/Mother/Offspring引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据