Advances in Neuroprotective Effects of Polymethoxyflavonoids
Polymethoxyflavonoids(PMFs),a class of flavonoids extracted from citrus plants,have a wide range of biological activities and neuroprotective effects.This article reviews the protective and ameliorating effects of PMFs on central nervous system injury(Alzheimer's disease,Parkinson's disease,cerebral ischemia,LPS-induced nerve injury,etc.)in animal and cell models,and focuses on its potential mechanism.The aim of this study is to further understand the pharmacodynamics and molecular mechanism of PMFs in deep,so as to provide new ideas for the prevention and treatment of nervous system related diseases.
polymethoxyflavonoidsnervous system injurytangeretinnobiletinsinensetinAlzheimer's disease(AD)Parkinson's disease(PD)
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