Red-emitting selenium-doped carbon dots for versatile applications in biosensing and antibacterial activities
In this study,we successfully designed and synthesized selenium-doped carbon dots(Se-CDs)using easi-ly available precursors of benzeneseleninic acid(BA)and o-phenylenediamine(o-PDA)through a one-step hydro-thermal method.These Se-CDs emitted red-wavelength fluorescence and were utilized to develop a sensitive fluores-cence sensor for detecting microRNA-21(miR-21).By incorporating deoxyribonuclease Ⅰ(DNase Ⅰ)-mediated signal amplification,the detection limit for miR-21 was improved from 78 to 6.8 nmol·L-1.Furthermore,we observed desirable inhibitory activity of the Se-CDs against Gram-negative bacteria of Escherichia coli(E.coli).