高密度自由羧基氧修饰孔壁的锌基金属有机骨架靶向电化学传感对乙酰氨基酚
Zinc metal-organic framework with high-density free carboxyl oxygen functionalized pore walls for targeted electrochemical sensing of paracetamol
续璐 1张丞雨 1籍文娟 1杨海英 2付云龙1
作者信息
- 1. 山西师范大学化学与材料科学学院,磁性分子与磁信息材料教育部重点实验室,太原 030032
- 2. 运城学院应用化学系,运城 044000
- 折叠
摘要
基于刚性苯多羧酸H4BPTC(联苯-3,3',5,5'-四甲酸),构筑了一例孔壁修饰高密度自由羧基氧的三维刚性锌基金属有机骨架:{[Zn2(BPTC)(H2O)(DMF)2]·DMF·H2O)n(SXNU-5-Zn).SXNU-5-Zn具有好的酸碱稳定性(pH=3～8)和热稳定性.以 SXNU-5-Zn构建了基于纯MOFs材料的电化学传感器(SXNU-5-Zn/GCE),其可高灵敏、选择性的检测对乙酰氨基酚(AC),检测的线性范围宽(0.02～765 μmol·L-1),检测限低至0.013 8 μmol·L-1(S/N=3).此外,所制备的SXNU-5-Zn/GCE传感器已成功应用于实际样品复方对乙酰氨基酚片中AC含量的检测.
Abstract
Based on the rigid benzene polycarboxylic acid H4BPTC(biphenyl-3,3',5,5'-tetracarboxylic acid),a 3D rigid zinc-based metal-organic framework with high-density free carboxyl oxygen modified pore walls,{[Zn2(BPTC)(H2O)(DMF)2]·DMF·H2O}n(SXNU-5-Zn),has been constructed.SXNU-5-Zn exhibited good acid-base stability within a pH range of 3-8 and excellent thermal stability.An electrochemical sensor,SXNU-5-Zn/GCE,based on a pure MOF material was constructed,which can detect paracetamol(AC)with high sensitivity and selectivity.The linear detection range spans from 0.02 to 765 μmol·L-1,with a limit of detection as low as 0.013 8 μmol·L-1(S/N=3).Furthermore,the prepared SXNU-5-Zn/GCE sensor has been successfully utilized to determine the AC content in compound acetaminophen tablets as an actual sample.CCDC:2320686.
关键词
金属有机骨架/锌/电化学传感器/对乙酰氨基酚Key words
metal-organic framework/zinc/electrochemical sensor/paracetamol引用本文复制引用
基金项目
运城市科技局基础研究项目(YCKJ-2020065)
出版年
2024
NETL
NSTL
维普
万方数据