摘要
通过水热法制备了锰、铋共掺杂铌酸钠压电骨修复材料.通过扫描电镜、X射线衍射仪、X射线光电子能谱仪、压电力显微镜、电化学工作站、紫外可见近红外光谱仪、电子顺磁共振波谱仪等对该材料的微观形貌、组成结构、压电性能、声动力性能和类酶活性等进行表征.结果表明,该材料兼具压电性能和类酶活性,超声触发压电响应不仅促进细胞增殖,而且增强声动力和类酶活性,产生活性氧,协同杀死细菌/清除生物膜.
Abstract
A bone repair material of Mn,Bi co-doped sodium niobate with piezoelectricity was prepared using the hydrothermal method.The microscopic morphology,composition,piezoelectricity,sonodynamic and enzyme-like activity of the material was characterized by scanning electron microscope,X-ray diffractometer,X-ray photoelec-tron spectrometer,piezoelectric force microscope,electrochemical workstation,ultraviolet-visible-near-infrared spectrometer,and electron paramagnetic resonance spectrometer.The results demonstrate that the material possess-es both piezoelectric properties and enzyme-like activity;the ultrasound-triggered piezoelectric effect not only pro-motes cell proliferation but also enhances sonodynamic and enzyme-like activity,which generates reactive oxygen species for synergistic killing of bacteria/removal of biofilm.