Piezoelectric effect of Mn,Bi co-doped sodium niobate for promoting cell proliferation and bacteriostasis
A bone repair material of Mn,Bi co-doped sodium niobate with piezoelectricity was prepared using the hydrothermal method.The microscopic morphology,composition,piezoelectricity,sonodynamic and enzyme-like activity of the material was characterized by scanning electron microscope,X-ray diffractometer,X-ray photoelec-tron spectrometer,piezoelectric force microscope,electrochemical workstation,ultraviolet-visible-near-infrared spectrometer,and electron paramagnetic resonance spectrometer.The results demonstrate that the material possess-es both piezoelectric properties and enzyme-like activity;the ultrasound-triggered piezoelectric effect not only pro-motes cell proliferation but also enhances sonodynamic and enzyme-like activity,which generates reactive oxygen species for synergistic killing of bacteria/removal of biofilm.
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维普
