Synthesis,crystal structures,and antibacterial activities of two zinc(Ⅱ)complexes bearing 5-phenyl-1H-pyrazole group
A novel compound(H2L)SCN(5-methyl-3-phenyl-2H-pyrazol-1-ium thiocyanate)has been obtained by the reaction of thiosemicarbazide with benzoylacetone in ethanol.Two zinc(Ⅱ)complexes[Zn(HL)2(NCS)(CH3COO)](1)and[Zn2(L)2(HL)2(NCS)2]2·2CH3OH(2)have been synthesized by the coordination reactions of Zn(OAc)2·2H2O or ZnCl2 with(H2L)SCN under reflux conditions.Elemental analyses and single-crystal X-ray diffraction have con-firmed the structures of the synthesized compounds.The(H2L)SCN ligand and complex 1 pertain to the triclinic sys-tem with space group P1,while complex 2 belongs to the monoclinic system with space group P21/n.Additionally,the antibacterial activities of the compounds were evaluated in vitro using the agar diffusion method against the bac-terial strains(Candida albicans,Staphylococcus aureus,and Escherichia coli).The results showed that the ligand exhibited relatively good antibacterial activities against the bacteria,and the complexes possessed stronger antibac-terial activities against the same bacteria than the free ligand.CCDC:2190252,(H2L)SCN;2190253,1;2190256,2.
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