Recent biological applications of corroles:From diagnosis to therapy
Corrole,a representative branch of porphyrin,has recently gained popularity.These molecules,viewed as ring-contracted porphyrinoids containing direct pyrrole-pyrrole linkages due to the absence of a meso-carbon atom,exhibit significant photo-physicochemical properties that make them attractive for various applications.Herein,this review comprehensively discusses the remarkable properties of corrole complexes,as well as related structures and chelation properties.It further explores the biological applications of corrole complexes for in vivo imaging and anti-cancer therapy.Additionally,it addresses common research bottlenecks and challenges,providing insights into future potential applications in disease diagnosis and treatment.Generally,this review aims to illuminate the signifi-cance of corrole complexes and their promising biological applications.
corrolemetallocorrolephotodynamic therapyin vivo imagingtheranostic