Research progress of near-infrared absorption inorganic nanomaterials in photothermal and photodynamic therapy of tumors
In recent years,non-invasive photothermal therapy(PTT)and photodynamic therapy(PDT)have been booming in the field of treating cancer.They offer many advantages over chemotherapy and other traditional cancer treatments.Among various types of PTT and PDT agents for cancer,some inorganic nanomaterials with different properties can achieve highly effective cancer PTT or PDT,because compared with other materials,they have the advantage of strong absorption in the near-infrared(NIR)window.In addition to being used alone,inorganic nano-materials can also be easily combined with other types of materials,chemical reagents,or drugs to construct multi-functional composite nano-therapeutic platforms.They are used to produce the synergistic effects of PTT,PDT,che-motherapy,and other therapies,enhance the therapeutic effect,and reduce toxicity and side effects to improve the cure rate of cancer patients.This review summarizes the latest research progress of common NIR inorganic nanoma-terials in the field of cancer PTT and PDT,involving metal nanoparticles,carbon nanomaterials,MXenes,transition metal oxides and chalcogenides,black phosphorus nanosheets,and complex nanomaterials.The PTT and PDT thera-peutic properties of these inorganic nanomaterials are mainly introduced.Finally,the research and development prospects of NIR inorganic nanosystems for cancer PTT and PDT in the future are put forward.
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