Crystal structures,DNA action,and antibacterial activities of three tetranuclear lanthanide-based complexes
Three new tetranuclear lanthanide-based complexes,namely[Ln4(dbm)6(L)2(μ2-OCH3)2(CH3OH)2]·xCH3OH[Ln=Eu(1),Tb(2),and Tm(3);x=3(1),0(2),and 0(3);Hdbm=dibenzoylmethane],were successfully designed and constructed by using a polydentate Schiff base(E)-2-hydroxy-3-methoxy-N'-(6-methoxy-pyridine-2-methylene)benzoylhydrazine(H2L)reacting with Ln(dbm)3·6H2O via solvothermal method.Single crystal X-ray dif-fraction analysis shows that the coordination units of 1-3 comprise four LnⅢ ions,six dbm-ligands,two L2-ligands two μ2-OCH3 ligands,and two coordinated CH3OH molecules.Four central LnⅢ ions are interlinked by six μ2-O atoms displaying a linear tetranuclear structure.Solid fluorescence tests show that 1 and 2 exhibited fluorescence emission peaks of Ln(Ⅲ)ions at room temperature.In addition,antibacterial studies indicate that 1-3 had stronger antibacterial activity than ligand H2L and Ln(Ⅲ)ions.The interaction between 1-3 and calf thymus DNA(CT-DNA)was studied by ultraviolet spectroscopy,cyclic voltammetry,and fluorescence spectrometry.The results indicate that 1-3 are primarily intercalated with CT-DNA.CCDC:2258753,1;2258754,2;2258756,3.
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