Synthesis,crystal structure,and DNA-binding of binuclear lanthanide complexes based on a multidentate Schiff base ligand
Two new dinuclear lanthanide(Ⅲ)complexes,namely[Ln2(dbm)2(HL)2(CH3OH)2]·4CH3OH[Ln=Tb(1)and Dy(2),Hdbm=dibenzoylmethane]have been synthesized using prepared multidentate Schiff base ligand H3L(hydroxy-acetic acid(4-diethylamino-2-hydroxy-benzylidene)-hydrazide)with good biological activity.Structure char-acterizations show that the complex comprises two Ln3+ions,two dbm-ions,two HL2-ligands,two CH3OH mole-cules,and four free methanol molecules.Each Ln3+ion is eight-coordinated.The two central Ln(Ⅲ)ions are bridged by two μ2-O atoms leading to a parallelogram[Ln2O2]core.The interaction between the compounds(H3L,1,and 2)and the calf thymus DNA(CT-DNA)has been further confirmed by UV-Vis spectrometry,fluorescence titration,and cyclic voltammetry.The results showed that both 1 and 2 could undergo insertion with CT-DNA.CCDC:2343005,1;2343006,2.
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