Applying real-time three-dimensional echocardiography and two-dimensional speckle tracking imaging to evaluation of left ventricular systolic synchrony in patients with preexcitation syndrome
Objective:To investigate the value of real-time three-dimensional echocardiography(RT-3DE)and two-dimensional speckle tracking imaging(2D-STI)applied to evaluating left ventricular systolic synchrony in patients with preexcitation syndrome.Methods:Thirty-five patients with preexcitation syndrome were included in case group,and another 35 healthy subjects undergoing physical examination in our hospital at the corresponding period were recruited in control group.2D-STI was used to measure the following parameters in 17 left ventricle(LV)segments,including the standard deviations of time to peak circumferential strain(Tcs-SD),longitudinal strain(Tls-SD),circumferential strain rate(Tcsr-SD)and longitudinal strain rate(Tlsr-SD).RT-3DE was used to synchronously record and analyze left ventricular end-diastolic volume(LVEDV),end-systolic volume(LVESV),ejection fraction(LVEF),volume-time curve(VTC)of the 17 segments,standard deviation(Tmsv16-SD)and maximum difference(Tmsv16-Dif)of the time to minimum systolic volume of the 16 LV segments,and those after correction(Tmsv16-SD%and Tmsv16-Dif%).Results:①The indicators,including Tcs-SD,Tls-SD,Tcsr-SD and Tlsr-SD,were higher in case group than in control group(P<0.001);②LVEDV and LVESV were higher in case group than in control group(P<0.001),yet the LVEF level remained no difference between groups(P>0.05);③Patients in the case group had higher levels of Tmsv16-SD,Tmsv16-Dif,Tmsv16-SD%and Tmsv16-Dif%than those in the control group(P<0.001).Conclusion:Left ventricular systolic asynchrony presents in patients with preexcitation syndrome.RT-3DE and 2D-STI can be used to quantify left ventricular systolic function in patients with preexcitation syndrome and effectively evaluate left ventricular systolic synchrony.