Objective:To assess the value of renal impairment(RI)and excessive high-density lipoprotein cholesterol(HDL-C)in predicting the prognosis of patients with acute ischemic stroke caused by large vessel occlusions(AIS-LVO)during endovascular therapy(EVT).Methods:The clinical data were retrospectively analyzed in AIS-LVO patients receiving EVT in our department between July 2018 and December 2022.The cases were divided into RI group and non-RI group based on estimated glomerular filtration rate(eGFR).Univariate and multivariate logistic regression models were used to analyze the correlation between RI and other potential risk factors and the prognosis of AIS-LV0 patients during EVT.ROC curve and AUC analysis were used to analyze the predictive value of RI combined with other possible risk factors on the 90-day prognosis.Results:A total of 248 patients were included in this study.Multivariate logistic regression analysis showed that RI,baseline ASPECTs,internal carotid artery occlusion and excessive HDL-C were independently correlated with 90-day prognosis(all P＜0.05).RI combined with excessive HDL-C could improve the predictive ability of 90-day prognosis(AUC=0.702,P＜0.001).Conclusion:Both RI and excessive HDL-C are independent risk factors for poor 90-day prognosis of AIS-LVO patients during EVT,and combined use of the two indicators can improve the predictive ability of 90-day prognosis.
维普
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