首页|桃核承气汤联合针刺改善气虚血瘀型脑卒中偏瘫患者上肢功能的临床研究

桃核承气汤联合针刺改善气虚血瘀型脑卒中偏瘫患者上肢功能的临床研究

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目的:探讨针刺联合桃核承气汤治疗气虚血瘀型急性缺血性脑卒中(AIS)患者上肢功能障碍的临床疗效.方法:选取淮南东方医院集团总医院2020 年6 月~2022 年5 月收治的110 例气虚血瘀型AIS患者,随机分为观察组(针刺联合桃核承气汤治疗组)和对照组(针刺治疗组)各55 例,疗程21 d.比较两组患者治疗前、治疗第21 天及治疗结束第 90 天Fugl-Meyer评分(FMA)、香港版偏瘫上肢功能测试(FTHUE-HK)评分、改良Barthel指数(MBI)、中医证候积分及血液黏度相关指标,记录治疗期间不良事件发生率.结果:观察组和对照组分别有54、52 例患者纳入研究.相较于对照组,观察组患者治疗第21 天和治疗结束第90 天FMA、FTHUE-HK和MBI评分升高,而中医证候总积分、HCT、FIB和D-Dimer水平下降(P<0.05).两组患者治疗期间不良事件发生率差异无统计学意义(3.7%vs.1.9%,P>0.05).结论:针刺联合桃核承气汤内服可明显改善气虚血瘀型AIS患者上肢运动功能,降低中医证候积分,提高AIS患者生活自理能力,其主要机制可能与降低患者血液高凝状态有关.
Clinical study on acupuncture plus Taohe Chengqi decoction in improving upper limb function in stroke patients with qi deficiency and blood stasis syndrome
Objective:To explore the clinical efficacy of acupuncture plus Taohe Chengqi decoction in treating upper limb dysfunction in acute ischemic stroke(AIS)patients with qi deficiency and blood stasis syndrome.Methods:One hundred and ten AIS patients with qi deficiency and blood stasis syndrome admitted to our hospital were included between June 2020 and May 2022,and were randomly divided into observational group and control group(respectively treated by acupuncture plus Taohe Chengqi decoction and acupuncture for 21 days,both n=55).Acomparison wasmadebetween twogroups of patients regarding their Fugl-Meyer Assessment(FMA)scores,FTHUE-HK scores,modified Barthel index(MBI)scores,Traditional Chinese Medicine(TCM)symptom scores,and blood viscosity-related indicators before treatment,on day 21 of treatment,and on day 90 post-treatment.The incidence of adverse events during the treatment was recorded.Results:In the observational group and control group,54 and 52 patients were included in the study respectively.Compared with the control group,patients in the observational group had increased FMA,FTHUE-HK and MBI scores on day 21 of treatment and on day90 post-treatment,while TCM symptom total scores and levels of hematocrit(HCT),fibrinogen(FIB)and D-Dimer decreased(all P<0.05).There was no statistically significant difference in the incidence of adverse events between two groups of patients during treatment(3.7%vs.1.9%,P>0.05).Conclusion:Acupuncture plus Taohe Chengqi decoction can significantly improve the upper limb motor function of AIS patients with qi deficiency and blood stasis syndrome,reduce TCM symptom scores,and improve their self-care ability.The primary mechanism may be related to the reduction of the hypercoagulable state in patients.

qi deficiency and blood stasis syndromestrokeTaohe Chengqi decoctionacupuncture

尚甲甲、方运葵、孙雪

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淮南东方医院集团总医院 康复医学科,安徽 淮南 2320001

气虚血瘀 脑卒中 桃核承气汤 针刺

安徽省卫生健康科研立项项目

AHWJ2022b003

2024

皖南医学院学报
皖南医学院

皖南医学院学报

CSTPCD
影响因子:0.695
ISSN:1002-0217
年,卷(期):2024.43(3)