Analysis on the clinical characteristics of high-resolution manometry in 90 patients with functional constipation
Objective:To investigate the difference of high-resolution anorectal manometry(HRAM)in patients of different gender,age and symptoms with functional constipation.Methods:Retrospective analysis was performed in 90 cases of functional constipation undergone HRAM in the gastrointestinal motility room of the Department of Gastroenterology of the Second People's Hospital of Wuhu.The characteristics of parameters were analyzed among groups.Results:HRAM showed that the age of male patients with constipation was older than that of females.The maximum systolic pressure of anal canal and the rectal defecation pressure of male were higher than those of females,and the difference was significant(P<0.01).The anal canal length was shorter in patients of 60 years old and above than in those of 35 years old and below(P<0.05),yet the initial sensory threshold,the defecation threshold and the maximum tolerance capacity were higher in patients aged 36-59 years and 60 years old than those of 35 years old and below(P<0.05).The initial sensory threshold and defecation threshold in 60 years and older group were also higher than those in 36-59 years old group(P<0.05).The rectal defecation pressure in the outlet obstruction type constipation group was higher than that in the non-outlet obstruction group(P<0.05),and the anal relaxation rate during defecation was lower than that in the non-outlet obstruction group(P<0.001).Conclusion:HRAM has certain guiding significance in the diagnosis and treatment of patients with functional constipation,and can be widely used in clinical practice.