不同年龄及月经状态女性正常乳腺ADC值的差异
Differences in ADC values of normal mammary gland in women of different ages and menstrual statuses
张爱娟 1李周丽 1吴莉莉 1闫娜 2朱乐乐 3陈基明1
作者信息
- 1. 皖南医学院第一附属医院弋矶山医院放射科,安徽 芜湖 241001
- 2. 皖南医学院第一附属医院弋矶山医院超声医学科,安徽 芜湖 241001
- 3. 皖南医学院第一附属医院弋矶山医院健康管理中心,安徽 芜湖 241001
- 折叠
摘要
目的:探讨不同年龄及月经状态女性正常乳腺表观扩散系数(ADC)值的差异及其临床意义.方法:收集2020年8月～2022年11月弋矶山医院因自觉"包块"、不适,MRI检查双侧乳腺健康受试者332例资料,根据年龄分为低年龄组(n=107)、中年龄组(n=114)、高年龄组(n=111).根据不同月经状态将受试者分为月经期(n=49)、增殖期(n=77)、分泌期(n=94)和绝经后(n=112).在西门子后处理站中测量正常乳腺ADC值,多次测量(ROI保持一致)取平均值,比较不同年龄及月经状态的乳腺ADC值差异.结果:高年龄组左右侧正常乳腺ADC值均低于中、低年龄组(P＜0.05),3组左右侧正常乳腺ADC值差异均无统计学意义(P＞0.05).绝经后双侧正常乳腺ADC值均低于月经期、增殖期及分泌期(P＜0.05),月经期、增殖期、分泌期及绝经后双侧正常乳腺ADC值差异均无统计学意义(P＞0.05).结论:不同年龄及月经状态下正常女性乳腺ADC值的差异及个体间的变异度较大,利用ADC值诊断女性乳腺疾病应考虑不同年龄及月经状态下的基线ADC值差异.
Abstract
Objective:To investigate the differences and clinical significance of apparent diffusion coefficient(ADC)value in normal mammary gland in women of different age and menstrual status.Methods:The data were collected from 332 healthy subjects undergone MRI examination in our hospital for bilateral breasts due to self-perceived"lumps"or discomfort between August 2020 and November 2022.The cases were initially divided into low-age group(n=107),middle-age group(n=114)and high-age group(n=111),and then further classified into menstrual phase(n=49),proliferative phase(n=77),secretory phase(n=94)and postmenopausal phase(n=112)by the different menstrual status.ADC of normal breasts was repeatedly measured while maintaining consistent ROIs in the Siemens post-processing workstation,and the measurements were then averaged to compare differences in breast ADC values among various age groups and menstrual statuses.Results:The ADC values of both left and right normal breasts in the high-age group were significantly lower than those in the middle-age and low-age groups(P＜0.05).There was no statistical difference between the ADC value of the left and right normal breasts among the low,middle and high group(P＞0.05).The ADC values of bilateral normal breasts in the postmenopausal period were significantly lower than those in the menstrual,proliferative,and secretory phases(P＜0.05).There was no significant difference in the ADC values of bilateral normal breasts among menstrual,proliferative,secretory and postmenopausal phases(P＞0.05).Conclusion:ADC values of normal breasts vary a lot in women of different ages and menstrual statuses,therefore,diagnosis of female breast conditions by ADC value should take the difference of baseline ADC value into consideration.
关键词
乳腺/磁共振成像/表观扩散系数/月经Key words
mammary gland/magnetic resonance imaging/apparent diffusion coefficient/menstruation引用本文复制引用
基金项目
皖南医学院中青年科研基金项目(WK2022F24)
芜湖市软科学项目(2022rkx23)
出版年
2024
NETL
NSTL
万方数据