Risk factors of new conduction block after TAVR in patients with pure aortic regurgitation
Objective:To investigate the risk factors of new conduction block after transcatheter aortic valve replacement(TAVR)with a new generation self-expanding valve in patients with pure aortic regurgitation.Methods:Sixty eight consecutive patients undergoing TAVR due to severe pure aortic regurgitation in the Heart Center of Yijishan Hospital of Wannan Medical College were initially recruited from November 2021 to September 2023 for cohort analysis.Finally,58 cases were included,and divided into conduction block group(n=23)and non-conduction block group(n=35)according to the occurrence of new conduction block after TAVR.Clinical data were collected and risk factors of new conduction block after TAVR in PNAR patients were analyzed by logistic regression.Results:The prevalence rate of diabetes was higher,the valve implantation depth was deeper,and the aortic root angle was larger in the conduction block group(all P<0.05).Multivariate logistic analysis showed that greater aortic root angle(OR=1.166;95%CI:1.029-1.321)and deeper valve implantation depth(OR=1.504;95%CI:1.055-2.144)were the risks associated with new onset conduction block after TAVR.Conclusion:This study shows that aortic root angle and valve implantation depth are associated with the new conduction block independently in patients with PAR undergoing TAVR.It is suggested that the interventional operative plan should be fully combined with the angle of aortic root before operation to evaluate the best depth of valve implantation during operation and minimize the risk of new conduction block after TAVR.