首页|不同剂量瑞马唑仑对老年患者麻醉诱导期血流动力学的影响

不同剂量瑞马唑仑对老年患者麻醉诱导期血流动力学的影响

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目的:分析不同剂量瑞马唑仑全麻诱导对老年患者血流动力学的影响.方法:选取安徽皖北煤电集团总医院2022年1~12月收治的全麻手术老年患者90例,随机均分为A、B、C组,分别给予0.2、0.3、0.4 mg/kg瑞马唑仑,比较麻醉效果及其对血流动力学的影响.结果:C组患者麻醉镇静速度最快,B组次之,3组间差异有统计学意义(P<0.05).3组患者每搏量指数在T0、T1、T2时均依次下降(P<0.05);T1时平均动脉压均低于T0、T2时(P<0.05);A组患者T1时心指数高于T0时(P<0.05),3组患者T2时心指数均低于T1时(P<0.05);A组患者T2时心率均高于T0、T1时(P<0.05).不同剂量麻醉诱导后,3组患者每搏量指数、心率及平均动脉压差异均无统计学意义(P>0.05);T0时B组患者心指数均高于A、C组(P<0.05);T1、T2时A、B组患者心指数均高于C组(P<0.05).结论:瑞马唑仑剂量0.3 mg/kg用于老年患者全麻诱导,麻醉诱导速度快且血流动力学更稳定.
Effects of different doses of rimazolam on the hemodynamics in elderly patients during anesthesia induction
Objective:To investigate the effects of different doses of remazolam on the hemodynamics in elderly patients during induction of anesthesia.Methods:Ninety patients undergoing general anesthesia were included in our hospital from January to December of 2022,and equally randomized to group A,B and C,to which the dose of remazolam was applied by 0.2 mg/kg,0.3 mg/kg and 0.4 mg/kg respectively.Then the anesthetic effect and hemodynamics after anesthesia were compared among groups.Results:Theanesthesia sedation worked the fastest in group C,followed by group B.The difference was significant among the three groups(P<0.05).The stroke volume index for the three groups of patients were decreased sequentially at T0,T1,and T2(P<0.05),and the mean arterial pressure was lower at T1 than at T0 and T2(P<0.05).The cardiac index in patients in group A were higher at T1 than T0(P<0.05),and the cardiac index were lower at T2 than at T1 in the three groups of patients(P<0.05).The heart rate was higher at T2 than at T0and T1 in patients in group A(P<0.05).No significant differences in stroke volume index,heart rate and mean arterial pressure were observed in the three groups after anesthesia induction with different doses(P>0.05),yet the cardiac index were higher in group B than in group A and C at T0(P<0.05),and the cardiac index were higher in group A and B than in group C at T1 and T2(P<0.05).Conclusion:0.3 mg/kg remazolam is recommended for general anesthesia induction in elderly patients,for this dose can not only achieve earlier anesthesia induction,but also make more stable hemodynamics.

elderly patientssurgeryremazolamgeneral anesthesia inductionhemodynamics

乔伟、崔萌、王先锋

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安徽皖北煤电集团总医院 麻醉科,安徽 宿州 234000

老年 手术 瑞马唑仑 全麻诱导 血流动力学

宿州市科技计划项目

SZSKJJZC045

2024

皖南医学院学报
皖南医学院

皖南医学院学报

CSTPCD
影响因子:0.695
ISSN:1002-0217
年,卷(期):2024.43(5)
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