Objective:To clarify the clinical characteristics and laboratory data of Kawasaki disease(KD)complicated with coronary artery dilatation so as to improve the understanding and early diagnosis of Kawasaki disease in clinic care,explore the clinical effect of symptom nursing,special medication nursing and psychological nursing of children with Kawasaki disease,and effectively reduce the occurrence of coronary artery lesions from this entity.Methods:The clinical data were reviewed in 87 children of KD admitted to and treated in the Department of Pediatrics of the Second Affiliated Hospital of Anhui Medical University between January 1,2019 and October 1,2022.Of the 87 cases,24 were complicated with coronary artery injury.The demographic characteristics,laboratory and imaging findings as well as other clinical data were analyzed in all patients.Multivariate logistic regression model and receiver operating characteristic(ROC)curve were used to respectively analyze the potential risk factors and predictive value for the risk factors of KD.Results:Of the 24 KD children,18(75％)were complicated with coronary artery injury(CAL).There was no statistical difference between the two groups in the clinical data,including the changes at the tips of the fingers(toes),enlarged cervical lymph nodes and other data(P＞0.05).The AUC by male,abdominal pain and vomiting for predicting CAL was 0.760(ranging from 0.7 to 0.9)(P＜0.05).These three indexes were independent risk factors for incidence of CAL in KD,and were in moderate diagnostic value.In terms of laboratory test data,the value of procalcitonin(PCT)was significantly different(P＜0.05).Echocardiography indicated that the number of cases of mitral regurgitation increased significantly.High quality nursing is helpful to improve the medication compliance,improve the clinical symptoms of patients with KD,reduce the incidence of adverse drug reactions,reduce the anxiety of family members,and improve the clinical nursing satisfaction.Conclusion:Boys with long-term fever accompanied by gastrointestinal symptoms and significantly increased PCT should be subjected to cardiac ultrasound examination,and male,abdominal pain and vomiting can be used as risk factors for determination of CAL in KD.
维普
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