Isopropyl alcohol as the solvent is widely used in chemical industry and laboratory, but at present, the monitoring and analysis method of isopropyl alcohol in air and waste gas in China has not been clearly defined. In this study, the concentration of isopropyl alcohol in air and exhaust gas was determined by head space gas chromatography. The minimum detectable concentration was 0. 03 mg/L, and no solvent pollution, and the results were accurate and easy to operate.