Poly-γ-glutamic acid(γ-PGA)is a naturalanion polymer,which is composed of repeating D-and/or L-glutamic acid residues linked through γ-glutamyl bonds between the α-amino of a glutamic acid and carboxy of an adjacent glutamic acid.It exhibits excellent biological properties,such as good water solubility,biodegradability,biocompatibility,edibility,non-toxicity and environment-friendly property.As an ideal new biomaterial,γ-PGA has been widely used in agriculture,en-vironmental protection,medicine,food,industry,cosmetics and many other fields.Therefore,γ-PGA has enormous applica-tion prospects and commercial values,and attracted wide attention of more and more researchers at home and abroad in re-cent years.In this review,the structure,biological characteristics,bacterial strains,biosynthesis related genes and applica-tions of γ-PGA are summarized.