首页|老年阻塞性睡眠呼吸暂停低通气综合征患者认知障碍风险预测模型构建与应用

老年阻塞性睡眠呼吸暂停低通气综合征患者认知障碍风险预测模型构建与应用

扫码查看
目的 分析老年阻塞性睡眠呼吸暂停低通气综合征患者发生认知障碍的危险因素,构建并验证预测模型的效果。方法 于2022年1月-2024年5月,便利选取在德阳市某三级医院就诊的212名老年阻塞性睡眠呼吸暂停低通气综合征患者作为本次研究对象,按照7:3的比例,将研究对象分为建模组(148例)和验证组(64例),通过Logistic回归分析探索认知功能障碍的危险因素,建立预测模型,通过Hosmer-Lemeshow拟合优度检验、ROC曲线下面积来判断模型的诊断价值。结果 212例患者中,认知障碍的发生率为38。7%;年龄、文化水平、体质量指数、血压、血脂、平均血氧饱和度进入预测模型。结论 年龄、文化水平、体质量指数、血压、血脂、平均血氧饱和度可以有效预测患者认知功能障碍的发生率。
Construction and Application of Risk Prediction Model of Cognitive Impairment for Elderly Patients with Obstructive Sleep Apnea-Hypopnea Syndrome
Objective To analyze the risk factors for cognitive impairment in elderly patients with Obstructive Sleep Apnea-Hypopnea Syndrome,and to construct and validate the effectiveness of a predictive model.Methods 212 elderly patients with Obstructive Sleep Apnea-Hypopnea Syndrome who visited a Grade-A hospital in Deyang City were conveniently selected as the research subjects from January 2022 to May 2024.The research subjects were divided into a modeling group(148 cases)and a validation group(64 cases)according to a 7:3 ratio.Logistic regression analysis was used to explore the risk factors of cognitive impairment,and a prediction model was established.The diagnostic value of the model was judged by Hosmer-Lemeshow goodness of fit test and ROC curve area.Results The incidence of cognitive impairment was 38.7%among the 212 patients.Age,educational level,body mass index,blood pressure,blood fat,and mean blood oxygen saturation are entered into the prediction model.Conclusion Age,educational level,body mass index,blood pressure,blood fat,and mean blood oxygen saturation can effectively predict the incidence of cognitive impairment in patients.

Obstructive Sleep Apnea-Hypopnea SyndromeCognitive impairmentElderlyRisk prediction model

李婷婷、赵天霞、陈瑶瑶、曾静

展开 >

德阳市人民医院,四川 德阳 618000

阻塞性睡眠呼吸暂停低通气综合征 认知障碍 老年人 风险预测模型

2025

卫生职业教育
甘肃省医学科学研究院

卫生职业教育

影响因子:0.39
ISSN:1671-1246
年,卷(期):2025.43(4)