Effect of Acupuncture Combined with Zengye Chengqi Decoction on Clinical Symptoms and Gastroin-testinal Function of Elderly Patients with Chronic Functional Constipation
Objective:To observe the effect of acupuncture combined with Zengye Chengqi Decoction on clini-cal symptoms and gastrointestinal function of elderly patients with chronic functional constipation.Method:Ninety cases of elderly patients with chronic functional constipation were selected and divided into lactulose group(45 ca-ses)and needle-medicine combination group(45 cases)by simple random method.The lactulose group was treated with lactulose oral solution,and the needle and medicine combination group was treated with acupuncture combined with fluid-enhancing Cheng Qi Tang on its basis for 3 consecutive courses of treatment.Compare the efficacy of the two groups and the differences in enteric neurotransmitters,intestinal flora,colonic transit time,Wexner constipa-tion score,and TCM evidence points before and after treatment.Results:The total effective rate was significantly higher in the needle-medicine combination group than in the lactulose group(93.33％vs 75.56％,P＜0.01).Growth inhibitin(SS)and Bifidobacterium and Lactobacillus were significantly higher in both groups compared to pre-treatment,and were higher in the needle-medicine combination group compared to the lactulose group(P＜0.01).After treatment,nitric oxide synthase(nNOS),vasoactive intestinal peptide(VIP),Enterobacteriaceae,yeast,left colonic transit time(LCTT),rectosigmoid transit time(RSTT),total colonic transit time(TCTT),and Wexner constipation scores and Chinese medicine evidence points were significantly lower in the two groups com-pared with those in the same group before treatment,while the combination of acupuncture and medication group was lower than the lactulose group(P＜0.01).Conclusion:Lactulose oral solution supplemented with acupuncture combined with fluid-enhancing Chengqi Tang can shorten colonic transit time,regulate intestinal flora,and improve gastrointestinal function in elderly patients with chronic functional constipation.
PrickZengye Chengqi TangChronic functional constipationIntestinal floraGastrointestinal function
NETL
NSTL
万方数据
