SII和MHR对Stanford B型主动脉夹层患者TEVAR术后发生院内MACE的预测价值
Predictive Value of SII and MHR for In-hospital Major Adverse Cardiovascular Events after TEVAR in Stanford Type B Aortic Dissection
文海越 1徐建辉2
作者信息
- 1. 武汉科技大学附属孝感市中心医院心血管内科,孝感 432003;武汉科技大学医学院,武汉 430062
- 2. 武汉科技大学附属孝感市中心医院心血管内科,孝感 432003
- 折叠
摘要
目的:探讨全身免疫炎症指数(SII)和单核细胞/高密度脂蛋白胆固醇比值(MHR)对Stanford B型主动脉夹层(TBAD)胸主动脉血管修复术(TEVAR术)后发生院内主要不良心血管事件(MACE)的预测价值.方法:回顾性分析2019-06-2023-06于孝感市中心医院接受TEVAR术治疗的145例TBAD患者的临床资料.根据患者院内MACE发生情况,将患者分成MACE组(n=30)和非MACE组(n=115).比较两组患者的临床资料,采用Logistic回归分析TBAD患者TEVAR术后发生院内MACE的危险因素,采用ROC曲线评估SII和MHR对TBAD患者TEVAR术后发生院内MACE的预测价值.结果:与非MACE组相比,MACE组入院白细胞计数、MHR、SII、TC/HDL升高,高密度脂蛋白胆固醇(HDL-C)降低,年龄较小(P＜0.05);多因素Logistic回归分析结果显示,较高水平的SII和MHR是TBAD患者TEVAR术后发生院内MACE的危险因素(P＜0.05).ROC曲线分析结果显示,SII和MHR均对TBAD患者TEVAR术后发生院内MACE具有预测价值(P＜0.05),SII灵敏度为 43.3％,特异度为 84.3％,AUC 为 0.669(95％CI 0.558-0.780,P＜0.05);MHR 灵敏度为 76.7％,特异度为57.4％,AUC 为 0.703(95％CI 0.640-0.797,P＜0.05);两者联合预测时灵敏度、特异度分别为 83.3％、61.7％,AUC 为 0.766(95％CI 0.682-0.849,P＜0.01),联合检测预测价值更高.结论:SII、MHR 对 TBAD 患者 TE-VAR术后院内MACE的发生具有预测价值,且两者联合预测价值更高.
Abstract
Objective:To explore the predictive value of systemic immune inflammation index(SII)and mon-ocyte count to high-density lipoprotein cholesterol ratio(MHR)for predicting in-hospital major adverse cardiovascu-lar events(MACE)after thoracic endovascular aortic repair(TEVAR)in Stanford B type aortic dissection.Meth-od:A retrospective analysis of clinical data from 145 patients with Stanford B type aortic dissection who underwent TEVAR treatment from June 2019 to June 2023 was conducted.Based on the occurrence of in-hospital MACE,the patients were divided into MACE group(n=30)and non-MACE group(n=115).The clinical data of the two groups was compared,and logistic regression analysis was used to evaluate the risk factors for in-hospital MACE af-ter TEVAR in patients with Stanford B type aortic dissection.The predictive value of SII and MHR for in-hospital MACE after TEVAR in patients with Stanford B type aortic dissection was evaluated using ROC curve analysis.Re-sults:Compared with the non-MACE group,the MACE group had higher levels of white blood cell count,MHR,SII,TC/HDL,and lower levels of HDL,as well as younger age(P＜0.05).Multivariate logistic regression analy-sis showed that higher SII and MHR were risk factors for the occurrence of in-hospital MACE after TEVAR in pa-tients with Stanford B type aortic dissection(P＜0.05).ROC curve analysis showed that both SII and MHR could effectively predict the occurrence of in-hospital MACE after TEVAR in patients with Stanford(P＜0.05).The sen-sitivity,specificity,and AUC were 43.3％,84.3％,and 0.669(95％CI 0.558-0.780,P＜0.05)for SII,and 76.7％,57.4％,and 0.703(95％CI 0.640-0.797,P＜0.05)for MHR,respectively.When combined for predic-tion,the sensitivity,specificity,and AUC were 83.3％,61.7％,and 0.766(95％CI 0.682-0.849,P＜0.01),which were superior to the predictive value of any single index for in-hospital MACE after TEVAR in patients with Stanford B type aortic dissection.Conclusion:SII and MHR have predictive value for the occurrence of in-hospital MACE after TEVAR in patients with Stanford B type aortic dissection,and their combined predictive value is higher.
关键词
Stanford/B型主动脉夹层/全身免疫炎症指数/单核细胞计数与高密度脂蛋白胆固醇比/主要不良心血管事件/风险预测/胸主动脉血管修复术Key words
Stanford type B aortic dissection/Systemic immune-inflammation index/Monocyte to high-den-sity lipoprotein cholesterol ratio/Major adverse cardiovascular events/Risk prediction/Thoracic endovascular aortic repair引用本文复制引用
基金项目
孝感市自然科学计划项目(XGKJ2020010029)
出版年
2024
NETL
NSTL
万方数据