Objective:To explore the therapeutic effect of medical ozone autotransfusion and enema on refrac-tory ulcerative colitis.Method:The clinical data of 73 patients with refractory enteritis who received medical ozone therapy from October 2018 to July 2023 were retrospectively analyzed.According to the treatment plan,the pa-tients were divided into medical ozone enema group of 34 cases and medical ozone autotransfusion combined with en-ema group of 40 cases(combination group).The therapeutic effect of the two groups was compared.Results:After completing one course of treatment,the modified Mayo scores of patients in both two groups were decreased signifi-cantly(P＜0.05).The total scores of physiological function,social function,psychological function and quality of life in the combination group were better than those in the enema group,and the differences were statistically signif-icant(P＜0.05).Serum CRP and IL-1β levels in combination group were significantly lower than those in enema group(P＜0.05).Conclusion:The combination of ozone autotransfusion and enema has a good therapeutic effect on patients with refractory enteritis.
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