食品与生物技术学报2024,Vol.43Issue(4) :17-24.DOI:10.12441/spyswjs.20231127001

益生菌对糖脂代谢紊乱相关疾病的缓解作用及机制

Alleviating Effect and Mechanism of Probiotics on Glycolipid Metabolism Disorder

姜金池 顾敏雯 苏印 丁思琪 姚源玥 崔洁 李文慧 胡永红
食品与生物技术学报2024,Vol.43Issue(4) :17-24.DOI:10.12441/spyswjs.20231127001

益生菌对糖脂代谢紊乱相关疾病的缓解作用及机制

Alleviating Effect and Mechanism of Probiotics on Glycolipid Metabolism Disorder

姜金池 1顾敏雯 2苏印 3丁思琪 2姚源玥 2崔洁 3李文慧 3胡永红1
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作者信息

  • 1. 南京工业大学食品与轻工学院,江苏南京 211816;南京工业大学材料化学工程国家重点实验室,江苏南京 211816
  • 2. 南京工业大学生物与制药工程学院,江苏南京 211816
  • 3. 南京工业大学食品与轻工学院,江苏南京 211816
  • 折叠

摘要

糖脂代谢紊乱是常见内源性疾病发病的重要因素,其相关疾病的发病率逐年上升,严重影响患者的生活质量.益生菌是对人体健康有益的微生物,可通过调节肠道微生物起到降低血糖、调节血脂、改善氧化应激及炎症的作用.作者综述了益生菌在高脂血症、糖尿病、高血压这3种糖脂代谢紊乱相关疾病中的具体作用效果及其相关机制.作为一种非药物性降糖、降脂方法,益生菌为糖脂代谢紊乱相关疾病的干预治疗提供了新思路.

Abstract

Disorder of glucose and lipid metabolism is an important factor contributing to the prevalence of common endogenous diseases,and the incidence of related diseases is increasing annually,severely impacting the quality of life of individuals.Probiotics,widely applied in daily foods as microorganisms beneficial to human health,can reduce blood glucose,regulate blood lipids,and improve the level of oxidative stress and inflammation by adjusting intestinal microbes.The author reviews the specific efficacy and relevant mechanisms of probiotics in three glucose-lipid metabolism disorder-related diseases,i.e.,hyperlipidemia,diabetes,and hypertension.As a non-drug therapy for reducing blood sugar and lipids,probiotic provides a new prospect for the intervention and treatment of diseases related to glucose and lipid metabolism disorders.

关键词

益生菌/肠道微生物/高脂血症/糖尿病/高血压

Key words

probiotics/gut microbiota/hyperlipemia/diabetes/hypertension

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基金项目

国家自然科学基金(32302045)

江苏省自然科学基金(BK20220333)

江苏省海洋科技创新项目(JSZRHYKJ202210)

出版年

2024
食品与生物技术学报
江南大学

食品与生物技术学报

CSTPCD北大核心
影响因子:0.674
ISSN:1673-1689
被引量1
参考文献量51
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