Tanning wastewater contains a large number of biodegradable organic pollutants and harmful substances,direct emissions seriously affect the ecological environment and human health.This paper takes the tanning wastewater as research object,it was treated with a cationic polyacrylamide(C-PAM)flocculant to optimize the treatment process parameters.The best process parameters for tanning wastewater treatment are determined by experimental study,the dosage of cationic polyacrylamide(C-PAM)is 1.5 mg/L,the pH of the tanning wastewater is 9,the settling time is about 20 min,and the optimal COD removal rate is 89.6%.