The 3-week-old C57BL/6 mice were treated with soybean isoflavones(SI).The morphology,antioxidant capacity and apoptosis of liver and kidney tissues were investigated,and the effects of SI on liver and kidney development in young mice were explored.The results showed that the percentage of body weight increasing in female mice is increased in a dose of SI dependent manner(P＜0.05),while male mice is decreased(P＜0.01).In female mice,SI treatment increases the antioxidant ability of liver and kidney(P＜0.05),and reduces the tissue damage of liver and kidney.In male mice,SI treatments decrease the antioxidant ability of liver(P＜0.01),but increase the antioxidant ability of kidney(P＜0.05).There is pathological damage to the liver,and no tissue damage to the kidney.It is suggested that young males should be cautious taking SI.
关键词
大豆异黄酮/幼年小鼠/肝肾/组织结构/抗氧化能力
Key words
soybean isoflavones/young mice/liver and kidney/organizational structure/antioxidant capacity
维普
万方数据