The chemical composition of the volatile oil from Paederia scandens was analysed by gas chromatography-mass spectrometer (GC/MS) technique.31 components,which constitute 77.16% the volatile oil,were identified and quantitatively determined.The content of 11 components was higher than 2%.They are:1-ethoxyl pentane,isopentyl acetate,benzaldehyde,ethyl hexanoate,phenylmethyl formate,phenylmethyl acetate,2-phenylethyl acetate,5,6,7,7a-tetrahydro-4,4,7a-trimethyl-2(4H)-benzofuranone,pentadecanoic acid ethyl ester,hexadecanoic acid,isopentyl decanoate.