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脾脏破裂切除术后对T细胞亚群的影响

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目的:为了解脾脏破裂切除后造成T细胞亚群的变化,探讨手术后对机体免疫功能的影响。方法应用流式细胞仪检测脾切除术前一天,术后一天、一周及术后1个月、及3个月的外周血中免疫细胞T细胞亚群CD3+、CD4+、CD8+的变化情况,并记录统计分析情况。结果通过对4个时间段两组研究对象外周血的检验统计结果分析,在4个时间段内的样品里,不同T细胞亚群数量有差异显著,具有统计学意义(P<0.05)。结论脾脏破裂切除后造成T细胞亚群数量显著降低,从一方面反应出机体免疫功能的下降。
The effects of T cell subsets after ruptured spleen resection
Objective:in order to understand the spleen rupture after resection caused the change of T cell subgroup, we explore the impact on the body's immune function after surgery. Methods:we used flow cytometry to test before splenectomy, postoperative day outside, and postoper-ative week 1 month, 3 months of peripheral immune cells called T cells subgroup of CD3 +, CD4 +, CD8 + and statistical analysis. Results:through the four period both groups peripheral blood test statistics results of the analysis of the four periods of sample different number of T cell subgroup, significant difference statistically significant (P<0.05).Conclusion:it is turn out that the body's immune function declined after resec-tion caused a significant decline ,which reflected in the number of T cell subgroup.

spleenAppendectomyImmune function

周靳

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武汉大学医学院-基础医学院,湖北 武汉 430071

湖北省孝感市中心医院急诊科,湖北 孝感 432000

脾脏 脾脏切除 免疫功能

2015

现代妇女(医学前沿)

现代妇女(医学前沿)

ISSN:
年,卷(期):2015.(1)
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