Application and research progress of metabolic engineering in butanol production
The low yield and productivity of butanol in the traditional fermentation inhibit the development of biobutanol industry. Metabolic engineering, which is based on the systems biology, provides a reasonable basis for the strain manipulation. This paper introduces the biosynthetic pathways of the butanol and summarizes the application and latest research progress of metabolic engineering in butanol production. The prospect of biobutanol application is also proposed.