This review focuses on the latest research progress on the application of silk fibroin-silver nanoparticle composite materials,such as membranes,hydrogels,fiber and other application forms,in the antibacterial field.The antibacterial advantages of the combination between silk fibroin and silver nanoparticle are expounded.The stability and safety issues of the silk fibroin-silver nanoparticle composite,which need to be solved urgently,are also described.The development direction of silk fibroin-silver nanoparticle composite materials in the future is prospected.