Sulfamethoxazole(SMX),an antibiotic,is taken as the test object to explore the efficiency of electrochemical synchronous ozone-generating system for degradation of antibiotics-containing wastewater and the degradation mechanism.Current intensity,sulfates content,and initial pH are selected as independent variables,and the degradation rate of SMX is determined by the Box-Behnken design method.Response surface analysis is employed to simulate and analyze the effect of each factor and their interaction on the degradation rate of SMX.The results show that the highest degradation rate of SMX is 99.705%within 30 min when the current intensity is 4.3 A,the content of sulfates is 0.27%,and pH is 5.59.The mechanism analysis shows that the main active substances in the system include O3,1 O2,·OH and·O-2,among which O3 and·OH play major roles.