Under the promotion of K2CO3/TiO2,thiophene is successfully converted to 2-thiophenic acid by carboxylation of carbon dioxide.The synthesis conditions are optimized,and the influences of the structure and properties of K2CO3/TiO2 promoter on the synthesis route are evaluated.The results show that the amorphous K2CO3 on the surface of K2CO3/TiO2 plays the major promotion role.Considering the thermal stability of the product,the reaction temperature should not exceed 300℃.The product is generated in large quantity within 1 hour at the beginning of the reaction,and the generation rate rapidly decreases thereafter.This study develops a novel,environmentally friendly,and efficient synthesis route for 2-thiophenic acid,and also expands the efficient utilization pathways for carbon dioxide.
关键词
2-噻吩甲酸/抗癌药中间体/二氧化碳/羧基化/合成
Key words
2-thiophenic acid/anticancer drug intermediate/carbon dioxide/carboxylation/synthesis
维普
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