氨基化明胶海绵的制备及其止血性能研究
Preparation of aminated gelatin sponges and study on their hemostatic properties
朱雨荷 1黄芳艳 1巨晓洁2
作者信息
- 1. 四川大学化学工程学院,四川 成都 610065
- 2. 四川大学化学工程学院,四川 成都 610065;四川大学高分子材料工程国家重点实验室,四川 成都 610065
- 折叠
摘要
对明胶进行氨基化改性,同时用京尼平和单宁酸作为交联剂进行交联反应,然后冷冻干燥得到了氨基化明胶海绵.结果表明,该海绵具有丰富的孔状结构以及快速吸水能力,同时能够通过静电相互作用增强与血细胞间的结合能力,使其具有优异的止血性能,为快速止血材料的制备提供了新方法.
Abstract
To prepare hemostatic materials with excellent hemostatic performance,the gelatin is modified through amination,and then cross-linked with tannic acid and genipin as cross-linking agents,followed by freeze-drying to obtain an aminated gelatin sponge.This sponge has a rich porous structure and rapid water absorption capacity.It can also enhance the binding ability with blood cells through electrostatic interactions,exhibiting excellent hemostatic performance,thus providing a new method for the preparation of rapid hemostatic materials.
关键词
止血海绵/氨基化明胶/京尼平/单宁酸/止血材料Key words
hemostatic sponges/aminated gelatin/genipin/tannic acid/hemostatic materials引用本文复制引用
出版年
2024
NETL
NSTL
万方数据