首页|氨基化明胶海绵的制备及其止血性能研究

氨基化明胶海绵的制备及其止血性能研究

Preparation of aminated gelatin sponges and study on their hemostatic properties

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对明胶进行氨基化改性,同时用京尼平和单宁酸作为交联剂进行交联反应,然后冷冻干燥得到了氨基化明胶海绵.结果表明,该海绵具有丰富的孔状结构以及快速吸水能力,同时能够通过静电相互作用增强与血细胞间的结合能力,使其具有优异的止血性能,为快速止血材料的制备提供了新方法.
To prepare hemostatic materials with excellent hemostatic performance,the gelatin is modified through amination,and then cross-linked with tannic acid and genipin as cross-linking agents,followed by freeze-drying to obtain an aminated gelatin sponge.This sponge has a rich porous structure and rapid water absorption capacity.It can also enhance the binding ability with blood cells through electrostatic interactions,exhibiting excellent hemostatic performance,thus providing a new method for the preparation of rapid hemostatic materials.

hemostatic spongesaminated gelatingenipintannic acidhemostatic materials

朱雨荷、黄芳艳、巨晓洁

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四川大学化学工程学院,四川 成都 610065

四川大学高分子材料工程国家重点实验室,四川 成都 610065

止血海绵 氨基化明胶 京尼平 单宁酸 止血材料

国家自然科学基金项目

21991101

2024

现代化工
中国化工信息中心

现代化工

CSTPCD北大核心
影响因子:0.553
ISSN:0253-4320
年,卷(期):2024.44(z2)