Trace oxygen-containing compounds such as methanol in light alkanes may cause unfavorable impact on the subsequent applications of light alkanes and the operation of industrial plants.Herein,n-hexane containing 1.2 wt.%methanol is used as model substrate to study the adsorption properties of methanol over CaCl2,sulfonated resin,microporous SiO2 and 4A zeolite,respectively by utilizing the unique reactivity of methanol and the polarity difference between methanol and n-hexane.Experimental results show that sulfonated resin represents high performance in removing methanol and good regeneration performance.Under the condition that methanol removal is higher than 90%,the adsorption capacity of methanol over sulfonated resin is 0.41 g·g-1.There is little change between regenerated sulfonated resin and fresh one,indicating reusability and good application prospect.