摘要
目的 基于澳大利亚乔安娜布里格斯研究所(JBI)循证卫生保健中心证据总结的方法学,针对癌症患者体力活动管理进行证据总结,为临床规范癌症患者的体力活动管理提供科学的依据.方法 依照证据"6S"金字塔模型检索相关文献,计算机检索BMJ Best Practice、UpToDate、JBI循证卫生保健中心数据库、Cochrane Library、全球各指南网站、癌症专业协会网站以及中英文相关数据库中关于癌症患者体力活动的所有证据.检索时限为2018年2月13 日—2023年2月13日.基于JBI循证卫生保健中心证据总结的方法学指导,由2名研究者对文献质量进行独立评价,并结合临床情境,提取符合标准的相关证据.结果 共纳入30篇文献,包括2篇指南、3篇专家共识、1篇证据总结、21篇系统评价、3篇随机对照试验,从体力活动获益、体力活动人群、体力活动前评估、体力活动方案实施、体力活动安全性监测、持续支持策略6个方面汇总了 29条最佳证据.结论 本研究在现有证据的基础上补充并更新了 15条证据,最终形成了癌症患者体力活动管理的最佳证据总结,能够为临床开展癌症患者的体力活动管理提供循证依据.证据大部分来自国外研究,建议我国学者在未来研究中使用相关证据时结合癌症患者的活动能力以及活动意愿,并考虑临床应用的具体情景,或开展基础研究进一步验证证据,以全面提高癌症患者的生活质量.
Abstract
Objective To summarize evidence for physical activity management in cancer patients based on the Joanna Briggs Institute(JBI)approach for evidence synthesis in health care,providing a scientific basis for the clinical standardization of physical activity management in cancer patients.Methods Literature was searched according to the"6S"pyramid model of evidence,using BMJ Best Practice,UpToDate,JBI Evidence-Based Practice Database,Cochrane Library,global guideline websites,professional cancer association websites,and relevant Chinese and English databases for all evidence regarding physical activity in cancer patients.The search covered the period from February 13,2018,to February 13,2023.Guided by the JBI approach for evidence synthesis,two researchers independently evaluated the quality of the literature and extracted relevant evidence in accordance with clinical scenarios.Results Thirty articles were included,comprising two guidelines,three expert consensuses,one evidence summary,21 systematic reviews,and three randomized controlled trials.A total of 29 best evidence points were summarized in six aspects:benefits of physical activity,physically active people,pre-activity assessment,implementation of physical activity programs,safety monitoring of physical activity,and ongoing support strategies.Conclusions This study supplements and updates 15 pieces of evidence based on existing evidence,ultimately forming a best evidence summary for the management of physical activity in cancer patients,providing evidence-based support for clinical management.Most evidence comes from international studies.It is recommended that Chinese researchers consider the activity ability and willingness of cancer patients when applying these findings in future research,and consider the specific clinical context,or conduct foundational research to further validate the evidence,to comprehensively improve the quality of life of cancer patients.
维普
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