Objective To conduct evidence-based exercise training for patients with peripheral arterial disease,develop review indicators,analyze barriers and enablers in the evidence-based practice process,and develop change strategies.Methods Guided by the clinical evidence application model of the Joanna Briggs Institute Evidence-Based Health Care Center,the study identified clinical nursing problems,formed the evidence-based practice team,systematically searched,evaluated,and summarized evidence of exercise training in patients with peripheral arterial disease,developed review indicators,and clarified review methods.The baseline review was conducted from October 1 to 31,2022.The integrated-promoting action on research implementation in health services(i-PARIHS)framework was used to analyze the barriers and enablers of the baseline review results,and corresponding strategies were formulated.Results A total of 20 best evidence were included,and 11 review indicators were developed,with only one indicator having a compliance rate of 100%.This study analyzed 22 barriers and 24 enablers,and formulated 14 change strategies.Conclusions The review indicators constructed based on the best evidence are scientific,effective,appropriate,and feasible.The analysis of barriers and enablers,as well as the formulation of change strategies,can provide guarantees for promoting clinical practice of exercise training for patients with peripheral arterial diseases.