Illness acceptance is a key factor regulating the psychosocial adaptation of patients with end-stage renal disease receiving replacement therapy,which directly affects patients'medication adherence as well as their self-management behaviors,and also plays an important predictive role in patients'physical and mental health and quality of life.This article elaborates on the measurement tools,current situation,influencing factors and intervention measures of disease acceptance in ESRD replacement therapy patients,and proposes prospects for future research,in order to provide a basis for the development of related researches on illness acceptance.