摘要
目的 对脑卒中患者早期活动的安全性及有效性进行系统评价再评价.方法 计算机检索中国知网、万方数据库、维普网、中国生物医学文献数据库、Cochrane Library、PubMed、Web of Science、CINAHL、Embase以及澳大利亚乔安娜布格里斯研究所循证卫生保健中心数据库有关脑卒中早期活动的系统评价,检索时限为建库至2023年5月.由2名研究人员独立进行文献筛选、资料提取,同时对纳入文献进行方法学质量评价,并进行证据汇总和分级.结果 共纳入10篇系统评价,方法学质量评价结果显示,1篇为中等质量文献,2篇为低质量文献,7篇为极低质量文献;证据质量评价结果显示,高质量证据3条,中等质量证据17条,低质量证据21条,极低质量证据17条.结论 早期活动有利于改善脑卒中患者的日常生活活动能力和肢体运动功能,降低并发症发生率,缩短住院时间,同时能在短期内提高患者的步行能力.但系统评价的证据质量均较低,仍需进一步改进早期活动干预措施的研究设计,为临床实践提供有力支撑.
Abstract
Objective To conduct an overview of systematic reviews on the safety and effectiveness of early mobilization in stroke patients.Methods Systematic reviews of early mobilization in stroke were electronically searched on China National Knowledge Infrastructure,WanFang Data,VIP,Chinese Biology Medicine,Cochrane Library,PubMed,Web of Science,CINAHL,Embase,and the Joanna Briggs Institute Evidence-Based Health Care Center Database.The search period was from database establishment to May 2023.Two researchers independently conducted literature screening,data extraction,and methodological quality evaluation of the included literature,as well as evidence summary and grading.Results A total of 10 systematic reviews were included.The methodological quality evaluation showed that one article was of medium quality,two articles were of low quality,and seven articles were of extremely low quality.The evidence quality evaluation indicated that there were three pieces of high-quality evidence,17 pieces of medium-quality evidence,21 pieces of low-quality evidence,and 17 pieces of extremely low-quality evidence.Conclusions Early mobilization is beneficial for improving the daily living ability and limb motor function of stroke patients,reducing the incidence of complications,shortening hospital stay,and enhancing their walking ability in the short term.However,the quality of evidence in the systematic review is relatively low,and further improvement is needed in the research design of early mobilization intervention measures to provide strong support for clinical practice.
基金项目
国家自然科学基金(71704074)
南京市卫生科技发展专项重点项目(ZKX21030)
南京大学中国医院改革发展研究院重点课题(NDYG2022006)
维普
万方数据