Objective To explore the current situation of resourcefulness among the primary caregivers of stroke patients and analyze its influencing factors.Methods From December 2020 to August 2021,convenience sampling was used to select 311 primary caregivers of stroke patients in the Neurology Department of three Class Ⅲ Grade A general hospitals in Yinchuan City as the research subject.A survey was conducted using the General Information Questionnaire,Resourcefulness Scale,Self-Rating Depression Scale,Chinese Perceived Stress Scale,Social Support Revalued Scale,and the Fatigue Scale-14.Results A total of 311 questionnaires were distributed and 308 valid questionnaires were collected,with a valid response rate of 99.04%.The resourcefulness score of the primary caregivers of 308 stroke patients was(83.98±12.85).The random forest model showed that when the λ-value was 1.667,the error was the smallest,and the corresponding number of influencing factors was 7.The independent variables ranked in the top 7 in importance were included in multiple stepwise regression.Multiple stepwise regression analysis showed that perceived stress,educational level,and fatigue were the main influencing factors on the resourcefulness of the primary caregivers of stroke patients,and the differences were statistically significant(P<0.05).Conclusions The main caregivers of stroke patients have a moderate level of resourcefulness and require certain attention.Nursing staff can collaborate with social workers and other personnel to provide support and assistance to caregivers,alleviate their physical and mental stress,thereby improving their resourcefulness and the quality of care.